Medivir – Emanuel Sidea
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The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further. MOUNTAIN VIEW, Calif., Jan 11, 2021 (GLOBE NEWSWIRE via COMTEX) -- MOUNTAIN VIEW, Calif., Jan. 11, 2021 (GLOBE NEWSWIRE) -- IGM Biosciences, Inc. (Nasdaq: Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir. Medivir recently renegotiated the original agreement with TetraLogic so that the compensation Medivir is obliged to pay in connection with a licensing agreement is based on the Birinapant is a project acquired in 2016 from TetraLogic Pharmaceuticals Corporation, subsequently developed by Medivir. At the end of 2020, we succeeded in renegotiating the birinapant agreement with TetraLogic so that the conditions for achieving an out-licensing were significantly improved. The terms of the agreement also entitle Medivir, should birinapant be successfully developed and approved, to receive milestone payments up to a total of approximately $350 million, plus tiered Birinapant was originally acquired by Medivir from TetraLogic in 2016.
- Medivir erhåller en upfront-betalning samt milstolpebetalningar och royalty - IGM ska utveckla birinapant i kombination med IGM-8444 för behandling av solida tumörer Stockholm — Medivir AB (publ) (Nasdaq Stockholm: MVIR) meddelade idag att bolaget har ingått ett exklusivt licensavtal som ger IGM Biosciences, Inc. (Nasdaq: IGMS) de globala och exklusiva rättigheterna att utveckla Stockholm - Medivir AB (publ) (Nasdaq Stockholm: MVIR) today announced that it has entered into an exclusive licensing agreement, through which IGM Biosciences, Inc. (Nasdaq: IGMS), will receive global, exclusive development rights for birinapant, a clinical-stage SMAC mimetic that binds to and degrades Inhibitors of Apoptosis Proteins (IAPs), leading to cell death (apoptosis) in tumor cells. Intresserad av ämnet Medivir? Här hittar du samtliga artiklar, kommentarer och analyser om Medivir från Dagens industris redaktion. Bevaka ämnet för att hålla dig uppdaterad om Medivir. Based on its unique design and mechanism, birinapant has the potential to enhance patients’ responses in combination with other treatments. Medivir’s initial focus is on developing birinapant in combination with an immuno-oncology agent. Stockholm — Medivir AB (Nasdaq Stockholm: MVIR) meddelar idag att den första patienten inkluderats i en fas I-studie där säkerhet och tolerabilitet av en kombination av birinapant och strålbehandling utvärderas i patienter med återfall av skivepitelcancer i huvud-halsregionen (HNSCC).
Det nya avtalet 11/10/2020 7:44:26 AM - Medivir tappar intäkter, men rapporterar vinst tack vare 10/4/2018 10:15:57 AM - Positiv interimsdata för Medivirs birinapant enligt 11 december 2020 – ”Medivir stärker förutsättningarna för affärsutveckling genom omförhandlat avtal med TetraLogic avseende birinapant”.
Medivir tecknar globalt licensavtal för birinapant
2021-01-11 STOCKHOLM, Oct. 4, 2018 /PRNewswire/ -- Medivir AB (Nasdaq Stockholm: MVIR) today announced safety and efficacy data following an interim analysis of phase I data from the ongoing phase I/II study of birinapant in combination with MSD's anti-PD-1 therapy, Keytruda® (pembrolizumab), in patients with advanced solid tumors who have exhausted available treatment options. Stockholm - Medivir AB (publ) (Nasdaq Stockholm: MVIR) today announced that it has entered into an exclusive licensing agreement, through which IGM Biosciences, Inc. (Nasdaq: IGMS), will receive global, exclusive development rights for birinapant, a clinical-stage SMAC mimetic that binds to and degrades Inhibitors of Apoptosis Proteins (IAPs), leading to cell death (apoptosis) in tumor cells. 2021-02-26 Birinapant (formerly TL 32711) is a synthetic, small molecule, bivalent mimetic of the second mitochondrial-derived activator of caspase (also called SMAC or Birinapant - Medivir AB - AdisInsight Either you have JavaScript disabled or your browser does not support Javascript .
Medivir AB ser. B Diskussion och forum Shareville
Medivir received a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials. In addition, the The agreement provided Medivir with a payment of USD 1 million after signing, which is to be followed by an additional USD 1.5 million when IGM includes birinapant in phase I clinical trials. Birinapant was originally acquired by Medivir from TetraLogic in 2016.
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2014, Feedback Forum Medivir will be hosting a Capital Markets Meeting Positive interim data on birinapant in combination with Keytruda®
Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir for the treatment of solid tumors. Medivir acquired birinapant from TetraLogic in 2016. The original agreement between Medivir and TetraLogic included milestone payments with predetermined amounts as well as royalty obligations to TetraLogic if and when Medivir develops, markets or out-licenses birinapant further. Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir. Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by Medivir.
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Januari - December Finansiell sammanfattning. Nettoomsättningen uppgick till 13,9 (8,7) MSEK. Pressmeddelande 21 december 2018 Stockholm - Medivir AB (Nasdaq Stockholm: MVIR) meddelade idag att den första patienten har doserats i fas 2 delen av BPT-201 studien av birinapant i kombination med Keytruda® (pembrolizumab). Medivir motivated the transition from its origin in retroviral drugs to oncology by it being a logical extension of their expertise in liver disease from earlier work on hepatitis C to this area.
Det ursprungliga avtalet mellan Medivir och TetraLogic innefattade bland annat milstolpesersättningar med förutbestämda belopp samt royalty-skyldigheter till TetraLogic om och när Medivir utvecklar, marknadsför eller utlicensierar birinapant vidare. Positive interim data on birinapant in combination with Keytruda® Stockholm, Sweden — Medivir AB (Nasdaq Stockholm: MVIR) today announced safety and efficacy data following an interim analysis of phase I data from the ongoing phase I/II study of birinapant in combination with MSD’s anti-PD-1 therapy, Keytruda® (pembrolizumab), in patients with advanced solid tumors who have exhausted
Medivir AB (publ) (Nasdaq Stockholm: MVIR) meddelade idag att bolaget har ingått ett exklusivt licensavtal som ger IGM Biosciences, Inc. (Nasdaq: IGMS) de globala och exklusiva rättigheterna att utveckla birinapant, ett SMAC-mimetikum i klinisk utvecklingsfas som binder till och bryter ned hämmare av apoptosproteiner (IAP), vilket leder till celldöd (apoptos) i tumörceller.
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Redeye expects a strong share price reaction to the surprise deal for the oncology 10 Feb 2021 Under the terms of the agreement, Medivir has granted Ubiquigent an Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM 9 Nov 2016 The acquisition includes remetinostat, a skin-directed histone deacetylase ( HDAC) inhibitor, and birinapant, a bivalent second mitochondrial 19 Apr 2021 parts of Medivir's business model, and the drug development is conducted either by Medivir or in partnership. Birinapant, a SMAC mimetic, Accelerated bookbuild offering - Joint bookrunner Medivir completion of the MIV-711 phase IIa study and the birinapant phase I/II study, start and completion of Birinapant is a SMAC mimetic that was acquired from TetraLogic Pharmaceuticals Corporation (TetraLogic) in 2016 and has since then been developed by 15 Oct 2018 Along with remetinostat, Medivir's clinical pipeline includes birinapant for solid tumours, MIV-818 for liver cancer and MIV-711 for osteoarthritis. 31 Mar 2021 Birinapant, a SMAC mimetic, is exclusively outlicensed to IGM Biosciences ( Nasdaq: IGMS) to be developed in combination with IGM-antibodies 27 Apr 2020 Birinapant was further studied using in vivo PDX models of TNBC and Smac mimetics like birinapant (TetraLogic Pharmaceuticals/Medivir) 30 Dec 2016 Medivir agreed to pay $12 million for the assets, which consist primarily of new drug candidates birinapant and SHP-141, plus milestone 28 Jan 2020 Medivir AB has announced that the independent safety committee (IDMC) for the phase II study of birinapant in combination with Merck and partners at Stockholm-based Medivir have previously tested an IAP inhibitor dubbed birinapant with Keytruda, only to shut the Phase II down @medivir Positive interim Phase 1 results delivered on #birinapant @Merck Keytruda combo #Clinicaltrial #oncology #biopharma #biotech #lifesciences Medivir AB. Sep 2014 - Mar 2019 4 years 7 months.